A placebo-controlled, blinded dose titration study was conducted in a total of 36 healthy, mature horses that were either Quarter horses or Thoroughbreds.
An induced adjuvant carpitis in the horse was used to assess the dose and efficacy of the intramuscular administration of Adequan® i.m.
The adjuvant induced arthritis was produced with a single intraarticular injection of 0.5 mL of Freunds adjuvant. The various treatments
comprised sterile saline solution as a placebo control and 50 mg, 125 mg, 250 mg, 500 mg and1,000 mg of the active drug substance Adequan® i.m.
dissolved in sterile water. Injections were given every 4 days for a total of 7 injections. Treatment followed a 10 day acclimation period and
a five day model induction period.1
Learn more about the science behind the dosing schedule. Read the Adequan® i.m. Technical Bulletin on dosing.