Healthy Joints

The healthy joint cycle1

In a healthy joint cycle, there is a natural "wear and repair" that keeps joint function in balance.1

The joint capsule has two distinct layers: an outer fibrous layer and an inner synovial membrane.

The synovial membrane also consists of two layers: a connective tissue layer that contains nerves and blood vessels and a thin lining that allows passage of blood components from the vascular layer into the joint.

Synovial (joint) fluid acts as the boundary lubricant of the joint capsule and synovial membrane to keep unwanted cells out of the joint cavity. It also removes waste and nourishes the cartilage.

Articular cartilage is a connective tissue that covers the ends of bones that is critical to the performance of joints. Dense fibers and a water-rich matrix give it “coil spring” resistance to pressure and shear forces (much like a shock absorber), and the ability to distribute loads evenly into subchondral bone. Cartilage cells repair and replace matrix components subjected to normal “wear and tear”.

Subchondral bone absorbs the forces of movement and carries away waste from the joint. It contains sensory nerves and blood vessels.

Adequan Equine horse healthy joint graphic solo

The healthy joint cycle for dogs

INDICATIONS Adequan® i.m. (polysulfated glycosaminoglycan) is recommended for the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses.
IMPORTANT SAFETY INFORMATION There are no known contraindications to the use of intramuscular Polysulfated Glycosaminoglycan. Studies have not been conducted to establish safety in breeding horses. WARNING: Do not use in horses intended for human consumption. Not for use in humans. Keep this and all medications out of the reach of children. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For full prescribing information, click here.
1. McIlwraith CW, Frisbie DD, Kawcak CE, van Weeren PR. Joint Disease in the Horse. St. Louis, MO: Elsevier, 2016; 33-48.

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